Xyloglucan Based In-Situ Gel: Formulation Development and Evaluation of In-Situ Ophthalmic Gel of Brimonidine Tartarate
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Thermo-Sensitive In Situ Gel of Brimonidine Tartrate
The intension behind the present work was formulation and evaluation of in situ gel of brimonidine tartrate. Brimonidine tartrate is an antiglaucomic agent which shows rapid precorneal exclusion and reduced ocular bioavailability when given in form of conventional ophthalmic formulations. To avoid this, an attempt has been made to formulate thermosensitive in situ gel of brimonidine tartrate to...
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The aim of the present study was to formulate and evaluate nystatin containing thermosensitive mucoadhesive gel for vaginal drug delivery to achieve prolonging the residence time, sustained drug release, enhancing efficacy, decreasing recurrence, and increasing patient compliance in the treatment for vaginal candidiasis. Here nystatin (1%) as a model drug. A 3 full factorial design was employed...
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In-situ forming polymeric formulations drug delivery systems is in solution form before administration in the body, but once administered, undergoes gelatin in-situ to form a gel. The formulation of gel depends upon factors like temperature modulation, pH changes, presence of ions and ultra-violet irradiation, from which drug gets released in sustained and controlled manner. The object of this ...
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The present study was aimed at formulating thermoreversible in situ gel of local anesthetic by using xyloglucan based mucoadhesive tamarind seed polysaccharide (TSP) into periodontal pocket. Temperature-sensitive in situ gel of lidocaine hydrochloride (LH) (2% w/v) was formulated by cold method. A full 3(2) factorial design was employed to study the effect of independent variables concentration...
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This study aimed to optimize and evaluate a thermoresponsive ophthalmic in situ gel containing curcumin-loaded albumin nanoparticles (Cur-BSA-NPs-Gel). Albumin nanoparticles were prepared via a desolvation method, and the gels were prepared via a cold method. The central composite design and response surface method was used to evaluate the effects of varying Pluronic F127 and Pluronic F68 conce...
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ژورنال
عنوان ژورنال: Indo Global Journal of Pharmaceutical Sciences
سال: 2018
ISSN: 2249-1023
DOI: 10.35652/igjps.2018.92103